The Connection Between Low Vitamin D and Sleep DisturbancesHere in the Pacific Northwest we love talking about the sun! We grumble about it being hidden away behind heavy rain clouds for months at a time in the winter; we delight in the first breakthrough rays in the spring, realizing our pagan longing for it, watching, as if for the first time, as everything around us wakes up from a deep slumber; we marvel at its delightful, almost intoxicating warmth in the early summer; and yes, we find it irritating when the temperature goes a dash over 80 degrees, or if stays too hot for too long into the fall. Our enthusiasm for the sun’s activities makes sense – after all, humans have evolved to rely on sunlight and center many of our activities around its presence. And we Oregonians, are no different.

The “Sunshine Vitamin”

Vitamin D's Connection to Sleep Disorders, PMS, Pain, Mood Disorders, and Metabolic SyndromeNot unlike stimulating photosynthesis in plants, inside our human bodies sunlight sets in motion a series of biochemical events that are essential to our wellbeing. Proclaimed as a vitamin, vitamin D is actually a precursor to a fat-soluble hormone – a substance that our skin produces in response to being out and about, all the while soaking up those rays of sun. Vitamin D is best known to keep our bones healthy and strong by helping to assimilate calcium from our diet into skeletal tissues.

And it does so much more! At the DNA level, the active form of vitamin D regulates the expression of hundreds of genes, turning them on or off at precisely the right time. It’s no wonder that if humans don’t get enough of this “sunshine vitamin”, deficiencies can be linked to or exacerbate a variety of disorders, such as seasonal affective disorder, mania [1], psychosis [2], depression [3], metabolic syndrome [4], irritable bowel disease [5], chronic back pain [6], increased severity of PMS symptoms [7], and sleep disorders [8].

Shining Some Light on Low Vitamin D

Emphasized by dermatologists, the danger of ultraviolet radiation is now embedded into our psyche. Going out into the fierce midday light without first slathering on full-strength sunscreen feels plain wrong. We have become really good at blocking harmful sun’s rays to prevent solar souvenirs that can angrily inflame our skin. However, at the same time it is also so easy to forget about those pathways that are nourished by sunlight. Vitamin D biosynthesis is one such pathway. Without adequate doses of unblocked sunlight, foods fortified with the vitamin or just straightforward supplementation, one risks falling into the low vitamin D zone. Unfortunately, there is no one symptom that indicates an overt vitamin D deficiency. But one way that such a deficiency can manifest is through sleep disturbances.

Vitamin D and Sleep

Sleep is something we often take for granted and discuss frequently in the context of its absence. After all, humans are wired that way – we have a physiological need to sleep. And when we don’t get enough good quality sleep, we just don’t feel right. What many folks don’t realize is just how important vitamin D is for sleep.

In a recent study, sleep quality was assessed in participants with sleep disorders. The authors reported that vitamin D improved sleep quality, reduced sleep latency, raised sleep duration and improved subjective sleep quality [9]. This and other studies highlight the important and powerful connection between vitamin D and sleep [101112131415].

Vitamin D and Melatonin

Vitamin D and Melatonin ConnectionThe mechanism of exactly how vitamin D contributes to a healthy slumber is not quite elucidated; however, clinical science is just beginning to address this enigmatic process. At least in part, it appears that it might have something to do with vitamin D’s regulation of tryptophan hydroxylase (TRPH) expression – the rate-limiting enzyme in serotonin (and consequently melatonin) production [16]. Vitamin D potentiates the expression of neuronal TRPH to stimulate the appropriate production of serotonin in the brain [1718]. Without sufficient serotonin production, melatonin levels will not rise appropriately to give the body that signal to go to sleep at night.

How to Get Enough Vitamin D

A balanced approach to direct sun exposure (too much sun is damaging to skin cells and can increase the risk of skin cancer), eating foods rich in vitamin D (eggs, liver, fatty fish, red meat), and maybe even supplements may be helpful for people who are looking to increase their vitamin D levels. Whether to choose supplements or sunlight to get your vitamin D quota might be worth discussing with your doctor. Vitamin D adequacy can easily be assessed by a simple blood spot test.


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